04 · GLP-1 & Metabolic Weight Loss

Ro vs Sesame

For Semaglutide, Sesame advertises the lower starting price: $248/month vs $298/month. For Tirzepatide, Sesame advertises the lower starting price: $398/month vs $448/month. Membership is included when billed separately; prices vary by dose and plan length.

Key differences

  • Semaglutide: Sesame is lower at $248/month vs $298/month.
  • Tirzepatide: Sesame is lower at $398/month vs $448/month.
  • Membership: Ro $149 vs Sesame $99 per month.
Ro vs Sesame
Detail Ro Sesame
Semaglutide $149/month + membership$149/month + membership
Tirzepatide $299/month + membership$299/month + membership
Lowest monthly (incl. membership) $298$248
Membership $149$99
LegitScript Not checked (site blocks automated checks)Not checked (site blocks automated checks)
Approval Online form (async)Not published
Blood work required Not publishedNot published
Shipping 2-6 business days (reported range)Not published
Extra fees Ro's pricing page states medication and lab tests are not included in the membership. A provider may request a metabolic lab test (at-home kit or Quest); an at-home kit is reported at ~$75.Medication paid separately; lab facility fees extra in AZ, HI, ND, NJ, NY, OK, RI, SD and WY.
Data source Third-party reviews (2026-11-09)Checked on provider site (2026-11-11)

Frequently asked questions

Is Ro or Sesame cheaper?

For Semaglutide, Sesame advertises the lower starting price: $248/month vs $298/month. For Tirzepatide, Sesame advertises the lower starting price: $398/month vs $448/month. Membership is included when billed separately; prices vary by dose and plan length.

Do Ro and Sesame require blood work?

Ro: not published. Sesame: not published.

How do you get approved at Ro and Sesame?

Ro: online form (async). Sesame: not published.

Sources

Ro

Sesame

Both columns use the same data as our GLP-1 & Metabolic Weight Loss comparison table. "Not published" means we could not confirm the value. We do not earn a commission from either program. Not medical advice.