04 · GLP-1 & Metabolic Weight Loss
PlushCare vs Sesame
PlushCare and Sesame don't both publish a monthly price for the same treatment, so we can't say which is cheaper.
Key differences
- There is no treatment with a confirmed monthly price at both programs, so price can't be compared directly.
- Only Sesame lists Semaglutide in our data.
- Only Sesame lists Tirzepatide in our data.
- Membership: PlushCare $19.99 vs Sesame $99 per month.
| Detail | PlushCare | Sesame |
|---|---|---|
| Semaglutide | Not published | $149/month + membership |
| Tirzepatide | Not published | $299/month + membership |
| Lowest monthly (incl. membership) | Not published | $248 |
| Membership | $19.99 | $99 |
| LegitScript | Not checked (site blocks automated checks) | Not checked (site blocks automated checks) |
| Approval | Video visit | Not published |
| Blood work required | Yes | Not published |
| Shipping | Not published | Not published |
| Extra fees | Medication and lab work not included; follow-up visit price not published. | Medication paid separately; lab facility fees extra in AZ, HI, ND, NJ, NY, OK, RI, SD and WY. |
| Data source | Checked on provider site (2026-11-11) | Checked on provider site (2026-11-11) |
Frequently asked questions
Is PlushCare or Sesame cheaper?
PlushCare and Sesame don't both publish a monthly price for the same treatment, so we can't say which is cheaper.
Do PlushCare and Sesame require blood work?
PlushCare: required. Sesame: not published.
How do you get approved at PlushCare and Sesame?
PlushCare: video visit. Sesame: not published.
Sources
PlushCare
- PlushCare: Weight loss
- ⚠ PlushCare does not publish a self-pay medication price, so it is listed but not ranked on price.
- ⚠ Lab work is often required (ordered to your preferred lab).
Sesame
- Sesame: Online weight loss program
- ⚠ Care plan billed every 28 days (13 charges a year).
- ⚠ Plan details below the headline were read via a page summary.