04 · GLP-1 & Metabolic Weight Loss

Amazon One Medical vs Sesame

For Semaglutide, Amazon One Medical advertises the lower starting price: $149/month vs $248/month. Membership is included when billed separately; prices vary by dose and plan length.

Key differences

  • Semaglutide: Amazon One Medical is lower at $149/month vs $248/month.
  • Only Sesame lists Tirzepatide in our data.
  • Membership: Amazon One Medical $0 vs Sesame $99 per month.
Amazon One Medical vs Sesame
Detail Amazon One Medical Sesame
Semaglutide $149/month$149/month + membership
Tirzepatide Not published$299/month + membership
Lowest monthly (incl. membership) $149$248
Membership $0$99
LegitScript Not checked (site blocks automated checks)Not checked (site blocks automated checks)
Approval Online form (async)Not published
Blood work required Not publishedNot published
Shipping Not publishedNot published
Extra fees Message visits $39, video visits $59; medication billed separately.Medication paid separately; lab facility fees extra in AZ, HI, ND, NJ, NY, OK, RI, SD and WY.
Data source Third-party reviews (2026-11-11)Checked on provider site (2026-11-11)

Frequently asked questions

Is Amazon One Medical or Sesame cheaper?

For Semaglutide, Amazon One Medical advertises the lower starting price: $149/month vs $248/month. Membership is included when billed separately; prices vary by dose and plan length.

Do Amazon One Medical and Sesame require blood work?

Amazon One Medical: not published. Sesame: not published.

How do you get approved at Amazon One Medical and Sesame?

Amazon One Medical: online form (async). Sesame: not published.

Sources

Amazon One Medical

  • Amazon: GLP-1 management program
  • One Medical: Weight loss care
  • ⚠ onemedical.com blocks direct access from our location; prices come from Amazon’s own pages and announcement as indexed by search.
  • ⚠ Amazon pages differ on the entry price ($39 vs $59); confirm in the app.
  • ⚠ Zepbound cash price not confirmed on these pages.

Sesame

Both columns use the same data as our GLP-1 & Metabolic Weight Loss comparison table. "Not published" means we could not confirm the value. We do not earn a commission from either program. Not medical advice.