04 · GLP-1 & Metabolic Weight Loss

Amazon One Medical vs PlexusDx

For Semaglutide, both advertise $149/month. Membership is included when billed separately; prices vary by dose and plan length.

Key differences

  • Semaglutide: both advertise $149/month.
  • Only PlexusDx lists Tirzepatide in our data.
Amazon One Medical vs PlexusDx
Detail Amazon One Medical PlexusDx
Semaglutide $149/month$149/month all-in
Tirzepatide Not published$189/month all-in
Lowest monthly (incl. membership) $149$149
Membership $0$0
LegitScript Not checked (site blocks automated checks)Active LegitScript seal on site
Approval Online form (async)Not published
Blood work required Not publishedNo
Shipping Not publishedFree 2-day shipping (official site)
Extra fees Message visits $39, video visits $59; medication billed separately.No hidden fees per PlexusDx; charged $0 unless a provider approves medication.
Data source Third-party reviews (2026-11-11)Checked on provider site (2026-11-10)

Frequently asked questions

Is Amazon One Medical or PlexusDx cheaper?

For Semaglutide, both advertise $149/month. Membership is included when billed separately; prices vary by dose and plan length.

Do Amazon One Medical and PlexusDx require blood work?

Amazon One Medical: not published. PlexusDx: not required.

How do you get approved at Amazon One Medical and PlexusDx?

Amazon One Medical: online form (async). PlexusDx: not published.

Sources

Amazon One Medical

  • Amazon: GLP-1 management program
  • One Medical: Weight loss care
  • ⚠ onemedical.com blocks direct access from our location; prices come from Amazon’s own pages and announcement as indexed by search.
  • ⚠ Amazon pages differ on the entry price ($39 vs $59); confirm in the app.
  • ⚠ Zepbound cash price not confirmed on these pages.

PlexusDx

Both columns use the same data as our GLP-1 & Metabolic Weight Loss comparison table. "Not published" means we could not confirm the value. We do not earn a commission from either program. Not medical advice.